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Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8

Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8

Overview Hot sell Intermediate Raloxifen e hydrochlo ride CAS 82640-04-8 Product Description R'aloxifene Hydrochloride i
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Description

Basic Info
Model NO. 82640-04-8
Powder Yes
Customized Non-Customized
Certification GMP, HSE, ISO 9001, USP, BP
Suitable for Elderly, Adult
State Powder
Purity >99%
Storage Condition Store at Rt
Transport Package Aluminium Foil Bag
Specification kg
Trademark FOUSI
Origin China
Production Capacity 100000kg/Month
Product Description

Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8


Hot sell Intermediate Raloxifen e hydrochlo ride CAS 82640-04-8

Product Description

Product NameRaloxifen e Hydrochloride
CAS NO.82640-04-8
Other NameRaloxifen e HCl
Molecular FormularC28H28ClNO4S
Molecular Weight510.044
AppearanceLIGHT YELLOW powder
Purity99%
Boiling Point728.2ºC at 760 mmHg
Meliting Point143-147ºC
Flash Point394.2ºC
Density1.285g/cm3

R'aloxifene Hydrochloride is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophe class of compounds. The biological actions of R'aloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (Agonism) and and the blockade of estrogenic pathways in other tissues (Antagonism).

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Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8

Product Parameters
ITEMSSPECIFICATIONRESULT
AppearanceLight Yellow PowderConform
SolubilitySoluble in 10% sodium hydroxid solution. Slightly Soluble in meth anol. Insoluble in waterConform
IdentificationsInfrared AbsorptionConform
ChlorideConform
TestsLoss on drying≤0.5%0.4%
Residue on ignition≤0.1%0.06%
Heavy metals≤10ppmConform
Related substancesR'aloxifene Impurity1≤0.20 %0.10%
Any unspecified individual impurity 2≤0.10%Max. 0.08%
Total impurities≤0.50%0.40%
AssayR'aloxifene HCl≥98.0%99.0%

Product Usage

(1) R'aloxifene is used to prevent and treat osteoporosis (condition in which the bones become thin and weak and break easily) in women who have undergone menopause (change of life; end of menstrual periods). R'aloxifene is also used to decrease the risk of developing invasive breast cancer (breast cancer that has spread outside of the milk ducts or lobules into the surrounding breast tissue) in women who are at high risk of developing this type of cancer or who have osteoporosis. R'aloxifene cannot be used to treat invasive breast cancer or to prevent invasive breast cancer from coming back in women who have already had the condition.

(2) R'aloxifene also cannot be used to decrease the risk of developing non-invasive breast cancer. R'aloxifene is in a class of medications called selective estrogen receptor modulators (SERMs). R'aloxifene prevents and treats osteoporosis by mimicking the effects of estrogen (a female hormone produced by the body) to increase the density (thickness) of bone. R'aloxifene decreases the risk of developing invasive breast cancer by blocking the effects of estrogen on breast tissue. This may stop the development of tumors that need estrogen to grow.

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Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8

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Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8

Hot Sell Intermediate Raloxifen E Hydrochloride CAS 82640-04-8

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